SARS-CoV-2 Envelope Simulation -- INCITE Proposal Meeting
Significant of Research - impact of COVID-19 on civilization - developing antibodies & preventing virus entry requires an understanding of the envelope (surface: spike protein, other elements, etc.) - there are lots of efforts studying individual components but we'd like to study the collective - cell-scale modeling Milesstones 1. Model envelope 2. Model envelope with initial encounter with host cell (binding to receptor) Title: "Modeling SARS-CoV-2 host cell encounter" Start with figures: - spike protein - overall model - protocell - life-cycle - initial encounter Arrange a meeting for next Monday, June 1st. Looks like I'm responsible for "Milestones and Objectives." We were leading the effort on the LRAC2020 proposal but to me that proposal was not completed on time. Though this was in part due to the time frame--attempting to complete it in a little over a week--we could have done a better job leading. This time, let's ...